Shiga Toxin Quik Chek Detection Of Shiga Toxin
RAPID DETECTION OF SHIGA TOXIN IN HUMAN FECAL SPECIMENS
The SHIGA TOXIN QUIK CHEK™ test is a rapid membrane enzyme immunoassay for the simultaneous qualitative detection and differentiation of Shiga toxin 1 (Stx1) and Shiga toxin 2 (Stx2) in a single test device from human fecal specimens and cultures derived from human fecal specimens.
TECHLAB® QUIK CHEK™
- Results in 30 minutes
- Single test cassette format
- Differentiation of Stx1 and Stx2 toxins
- LOD is 0.04ng/ml for Stx1 and 0.04 ng/ml for Stx2
Performance Data:
- In comparative studies for human fecal specimens
- Stx1 a sensitivity of 98.0%, a specificity of 99.8% and an overall correlation of 99.7% with cytotoxin assay
- Stx2 a sensitivity of 98.0%, a specificity of 100% and an overall correlation of 99.9% with cytotoxin assay
- In comparative studies for overnight broth cultures
- Stx1 a sensitivity of 100%, a specificity of 99.5% and an overall correlation of 99.5% with cytotoxin assay
- Stx2 a sensitivity of 95.70%, a specificity of 99.9% and an overall correlation of 99.6% with cytotoxin assay
Shiga toxin-producing Escherichia coli (STEC) cause foodborne and waterborne diarrheal disease that can progress to hemorrhagic colitis and hemolytic uremic syndrome (HUS). STEC derive their name from their ability to produce toxins (Stx1 & Stx2) similar in structure and function to the Shiga toxin produced by Shigella dysenteriae.
STEC strain O157:H7 has historically been the focus of attention in the United States, where it was first isolated from undercooked hamburgers. STEC infections caused by non-O157 strains have become more prevalent in recent years, both in the U.S. and globally. Since certain treatments and medications can increase the risk of HUS, prompt detection of STEC is necessary to prevent outbreaks and secondary transmission.
Ordering Details
Product Code: TLI-T30625 SHIGA TOXIN QUIK CHEK® (25 tests)
